Solution:Secretin is synthesized in cytoplasmic secretory granules of S-cells, which are found mainly in the mucosa of the duodenum. It is released into circulation and/or intestinal lumen in response to acidity (low duodenal pH), which is due to hydrochloric acid in the chyme that enters the duodenum from the stomach.
Its primary function is to neutralize the pH in the duodenum, allowing digestive enzymes from the pancreas to function optimally.
Enterogastrone is a hormone secreted by the mucosa of the duodenum (first section of the small intestine) in the lower gastrointestinal tract when fatty acids are in the stomach or small intestine. It inhibits the caudal (forward, analward) motion of the contents of chyme.